Conditions that might impair mucociliary clearance

The following conditions might decrease the ability of patients to expectorate secretions.  The cause is either secretions that are too thick and tenacious to bring up, or destruction of the cilia.

Diseases that impair mucociliary clearance are:

• Cystic Fibrosis
• Primary ciliary dyskinesia
• Bacterial infections
• Mycoplasmal infections
• Viral infections
• Bronchiectasis
• Chronic Obstructive Pulmonary Disease (mainly the chronic bronchitis component)
• Smoking (either passive or active)
• Lung transplantation

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