My answer: Actually, this question must be a common one, because in the April, 2014, edition of "Respiratory Care" a study by Maccari et al studied this exact thing. They gave breathing treatments to patients on and off noninvasive ventilation devices (Bi-Level and CPAP), and to patients not receiving NIV. The concluded that there was no difference in lung distribution.
- Maccari, et al, "Nebulization During Spontaneous Breathing, CPAP, and Bi-Level Positive-Pressure-ventilation: A Rondomized Analysis of Pulmonary Radioaerosol Deposition," Respiratory Care, April, 2014, volume 59, number 4, pages 479-484
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