Your question: I have a question about adjusting IPAP and EPAP. How do I know when I need to adjust both?
My answer: Think of it this way:
1. IPAP is the same as Pressure support = increased ventilation = blow off more CO2
2. EPAP is the same as PEEP/CPAP = increased FRC = increased oxygenation
So when you want to blow off CO2 you increase IPAP, and when you want to increase oxygenation you increase EPAP
Normal starting settings are IPAP 10 EPAP 4